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Cytek Biosciences
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Qiagen
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Qiagen
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Qiagen
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Qiagen
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Rockland Immunochemicals
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Cusabio
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highQu Inc
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Cell Signaling Technology Inc
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Image Search Results
Journal: Nature Communications
Article Title: GPR4 promotes immune exclusion in colon cancer through LOXL2-mediated extracellular matrix remodeling
doi: 10.1038/s41467-025-67967-z
Figure Lengend Snippet: A GPR4 regulates JAK2 and STAT3 phosphorylation via western blotting. n = 3. Scale bar: 100 µm. B Representative IF images of STAT3-Y705 phosphorylation regulated by GPR4. C Quantitative analysis of STAT3-Y705 phosphorylation in GPR4 - OE SW480 cell line and ( D ) GPR4 - KD HCT116 cell lline. Data are presented as mean ± SD. Two-tailed t test, n = 3 biologically independent samples. E Static treatment reduces both pSTAT3-Y705 and the expression of LOXL2, COL1A1, and TGF-β in GPR4 - OE SW480 cells. F RT-PCR analysis for LOXL2 in SW480 cell lines after receiving Stattic treatment. Two-tailed t test, n = 3 biologically independent samples. G RT-PCR analysis for TGF-β in SW480 cell lines after receiving Stattic treatment. Data are presented as mean ± SD.Two-tailed t test, n = 3 biologically independent samples. H STAT3 transcription factor binding site. I In SW480 cells, STAT3 binds to the LOXL2 promoter region confirmed via ChIP assays. J STAT3 binds to the TGF-β promoter region confirmed via ChIP assays. K RT-PCR assesses the transcriptional activity of LOXL2 promoter regions and TGF-β promoter region L . Data are presented as mean ± SD. Two-tailed t test, n = 3 biologically independent samples. ns > 0.05.
Article Snippet: Subsequently,
Techniques: Phospho-proteomics, Western Blot, Two Tailed Test, Expressing, Reverse Transcription Polymerase Chain Reaction, Binding Assay, Activity Assay
Journal: Experimental and Therapeutic Medicine
Article Title: Circulating levels of DDIT4 and mTOR, and contributions of BMI, inflammation and insulin sensitivity in hyperlipidemia
doi: 10.3892/etm.2022.11602
Figure Lengend Snippet: Comparisons of DDIT4, mTOR, and inflammatory factors between the two groups.
Article Snippet: The serum concentrations of
Techniques:
Journal: Experimental and Therapeutic Medicine
Article Title: Circulating levels of DDIT4 and mTOR, and contributions of BMI, inflammation and insulin sensitivity in hyperlipidemia
doi: 10.3892/etm.2022.11602
Figure Lengend Snippet: Correlations among clinical data and metabolic and inflammatory parameters.
Article Snippet: The serum concentrations of
Techniques:
Journal: Experimental and Therapeutic Medicine
Article Title: Circulating levels of DDIT4 and mTOR, and contributions of BMI, inflammation and insulin sensitivity in hyperlipidemia
doi: 10.3892/etm.2022.11602
Figure Lengend Snippet: Results of the principal component factor analysis with a Varimax rotation among subjects with hyperlipidemia.
Article Snippet: The serum concentrations of
Techniques: